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Acyl-CoA synthetase，ACS

Acetylcoenzyme A synthetase (ACS, EC 6.2.1.3)catalyzes the formation of acetyl coenzyme A with free fatty acids and coenzyme A. The ACS provided by our company is gene recombinant protein.Itis of high purity and good activity.

Biochemical studies: Free fatty acids(NEFA) in serum are seldom. Most of the free fatty acids binds with albumin. NEFA is directly related to oxidativestress, which can lead to the occurrence of diabetes by damaging of pancreaticislet cells and reducing peripheral tissue’s sensitivity to insulin.

Highconcentration of free fatty acid can lead to diabetes, severe liver disease,hyperthyroidism and other diseases, such as insulin resistance type /II diabetes, obesity, metabolic syndrome, andcardiovascular disease.

Enzymatic detection offree fatty acids is h rapid and simple. And at the sametime it has the advantages ofhigh sensitivity and easy automation, etc. ACSis the first enzyme of free fatty acid enzyme detection kit, so it plays a very important role in this kit .

Productdescription:

Appearance: Whitepowder, lyophilized

Preservationsolution: Tris buffer, pH8.0

Specific activity: 30U/mg protein

Unit definition: Oneunit will convert 1μmolof freefatty acids and coenzyme A to acetyl coenzyme Aper min at pH 7.5 at 37℃.

Basicinformation:

Cas#: LM-102

Source: Recombinantexpression

MMolecularweight: About 70kDa (SDS-PAGE detection)

Purity: 90%(SDS-PAGE test)

Storage: 4℃,store at -20℃ for long-term preservation Transportation: Coldpacks

Transportation: Coldpacks

Safety tips: Donot use for human experiments