Details

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GP73（GOLM1）

Golgi membrane protein 1, also known as Golgi membraneprotein GP73, Golgi phosphoprotein 2 and GOLM1, is a protein which belongs tothe GOLM1 / CASC4 family. GP73 is widely expressed. It is highly expressedin colon, prostate, trachea and stomach. It is expressed at lower level intestis, muscle, lymphoid tissues, white blood cells and spleen. It ispredominantly expressed by cells of the epithelial lineage. GP73 is expressedat low level in normal liver. Expression significantly increases in virus (HBV,HCV) infected liver. Expression of GP73 does not increase in liver disease dueto non-viral causes (alcohol-induced liver disease, autoimmune hepatitis).Increased expression in hepatocytes appears to be a general feature of advancedliver disease. In liver tissue from patients with adult giant-cell hepatitis(GCH), GP73 is strongly expressed in hepatocyte-derived syncitial giant cells. GP73is constitutively expressed by biliary epithelial cells but not by hepatocytes.

The GP73 provided by ourcompany is a recombinant protein expressed by mammalian cells, with highpurity, good immunogenicity and high biological activity.It was verified to be a ideal biologicalraw material for IVD.Antibody to this antigen protein can be usedas the core material of liver cancer early diagnosis kit and the protein itselfcan also be used as calibration items.

Product details：

Cas#:	LM207
From:	liquid
Constituents:	Recombinant human GP73 was dissolved in 1 xPBS(pH7.4)
Concentration:	1-2mg/ml
Shipment:	ice bag
Source:	A DNA sequece encoding the human GP73(NM_016548.3) extracellular fused with a affinity tag was expressed by HEK293 cells.
Molecular weight:	Recombinant human GP73 migrates as approximately 66-70 kDa band in SDS-PAGE under reducing conditions.
Purity:	>85% (determined by SDS-PAGE)
Storage:	4℃ for frequent usage,-20℃ for long-term storage. Avoid repeated freeze-thaw cycles.
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